ENHANCED ANTICANCER EFFICACY OF DUAL DRUG-LOADED SELF-ASSEMBLED NANOSTRUCTURED LIPID CARRIERS MEDIATED BY PH-RESPONSIVE FOLIC ACID AND HUMAN-DERIVED CELL PENETRATING PEPTIDE DNP2

The poor ability of recognition and penetration of chemotherapeutic agents to tumor cells are still great challenges for targeted breast cancer treatment.Herein, we established a tumor-targeted nanostructured lipid copyright encapsulating gambogic acid (GA) and paclitaxel (PTX), which was co-modified with acid-cleavable folic acid (cFA) and a human

For more than 10 million years, large, herd forming ruminants have thrived as parts of sustainable grazing ecosystems.Conversely, since their domestication 8,000–11,000 years ago, cattle, sheep, and goats have often exhibited dysfunctional relationships with the ecosystems they inhabit.A considerable literature, developed over decades, documents

Understanding stability of representation in the visual system can Building Set benefit by use of non-static, naturalistic stimuli.Here One-of-a-kind Hair-On Hides the authors examine stability of neural representations along the rat ventral stream while viewing naturalistic and synthetic movies.